Tissue Viability

SSIs are the third most commonly reported type of healthcare-acquired infection and the most costly1. They place a significant impact on patient welfare2 as well as presenting a heavy financial burden for the NHS.3

Leukomed® Sorbact® is an innovative post-operative film dressing with a purely physical mode of action, used to prevent surgical site infection (SSI) in closed surgical wounds. Following rigorous assessment by leading clinical and health economic experts during the NICE Medical Technology appraisal process it is proposed that Leukomed Sorbact should be considered as an option for preventing surgical site infection (SSI) in wounds with low to moderate exudate after caesarean section and vascular surgery. It should be used as part of usual measures to help reduce the risk of surgical site infection*.

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Potential cost savings of up to £6.5 million for the NHS

NICE reviewed cost modelling and concluded that using Leukomed Sorbact for wounds post caesarean section and vascular surgery could result in combined cost savings of up to £6.5 million by reducing the number of patients needing to stay in hospital for treatment of an SSI*.

In addition, the evidence reviewed suggests that Leukomed Sorbact:

  • reduces SSI in caesarean section and vascular surgery
  • may reduce antibiotic use
  • may reduce readmissions from wound complications

Cost savings are anticipated as Leukomed Sorbact is expected to reduce re-admissions and shorten the length of stay in hospital. For more details see the NICE resource impact report*.

Reducing SSI rates can reduce readmissions, antibiotic use, offer cost savings and benefit patient quality of life.4

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Supported by clinical evidence

The clinical evidence considered by NICE suggests that Leukomed Sorbact can reduce SSI risk in patients post caesarean section by up to 67% versus standard of care6,7, and by up to 42% in patients post vascular surgery.8,9

For more information on Leukomed Sorbact and the support available, please contact us here

*© NICE 2021 Leukomed Sorbact for preventing surgical site infection.
Available from www.nice.org.uk/guidance/mtg55. All rights reserved. Subject to Notice of rights.
NICE guidance is prepared for the National Health Service in England. All NICE guidance is subject to regular review and may be updated or withdrawn. NICE accepts no responsibility for the use of its content in this product/publication.


Medical references
1Wounds UK (2020) Best Practice Statement: Post-operative wound care – reducing the risk of surgical site infection. Wounds UK, LondonCcc
2Taylor L, Mills E, George S, Seckam A (2020) Reducing SSI rates for women birthing by caesarean section. J Community Nurs 34(3): 50–3
3Jenks PJ, Laurent M, McQuarry S, Watkins R. Clinical and economic burden of surgical site infection (SSI) and predicted financial consequences of elimination of SSI from an English hospital. J Hosp Infect 2014; 86(1):24–33. https://doi.org/10.1016/j.jhin.2013.09.012
4Totty JP, Moss JWE, Barker E, et al. (2020) The impact of surgical site infection on hospitalisation, treatment costs, and health related quality of life after vascular surgery. Int Wound J. 2020;1–8. https://doi.org/10.1111/iwj.
5NICE Resource impact report: Leukomed Sorbact for preventing surgical site infection (MTG55) (2021). https://www.nice.org.uk/guidance/mtg55/resources/resource-impact-report-pdf-9011234413
6Stanirowski et al. (2016a). Randomized Controlled Trial Evaluating Dialkylcarbamoyl Chloride Impregnated Dressings for the Prevention of Surgical Site Infections in Adult Women Undergoing Cesarean Section. SURGICAL INFECTIONS; 17(4): 427-435
7Stanirowski PJ., et al. (2016b). Stanirowski PJ., et al. (2016b). Dialkylcarbamoyl chloride-impregnated dressing for the prevention of surgical site infection in women undergoing cesarean section: a pilot studyArch Med Sci 2016;12(5): 1036–1042Arch Med Sci 2016;12(5): 1036–1042
8Bua. N et al. 2017 Dialkylcarbamoyl Chloride (DACC) Dressings in the Prevention of Surgical Site Infections After Non-implant Vascular Surgery: Annals of Vascular Surgery; 44: 387–392 dx.doi.org/10.1016/j.avsg.2017.03.198  2017 Elsevier Inc. All rights reserved. Manuscript received: October 11, 2016; manuscript accepted: March 28, 2017; published online: 5 May 2017
9Totty, J et al. (2019) Int Wound J. 2019;1–8.